Lactulose
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00581 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 76 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | acute urate nephropathy | KG + DL |
| 2 | nephrolithiasis | KG + DL |
| 3 | obstructive jaundice | KG + DL |
| 4 | bile duct disease | KG + DL |
| 5 | biliary tract disease | KG + DL |
| 6 | hyperphosphatemia (disease) | KG + DL |
| 7 | exercise-induced malignant hyperthermia | KG + DL |
| 8 | bile duct neoplasm | KG + DL |
| 9 | iron deficiency anemia | KG + DL |
| 10 | opiate dependence | KG + DL |
| 11 | nephrolithiasis susceptibility caused by SLC26A1 | KG + DL |
| 12 | cholelithiasis | KG + DL |
| 13 | urolithiasis | KG + DL |
| 14 | familial visceral myopathy | KG + DL |
| 15 | periodic paralysis (disease) | KG + DL |
| 16 | malignant hyperthermia, susceptibility to | KG + DL |
| 17 | gallstones | KG + DL |
| 18 | X-linked centronuclear myopathy | KG + DL |
| 19 | familial periodic paralysis | KG + DL |
| 20 | hypokalemic periodic paralysis | KG + DL |
| 21 | cholestasis, intrahepatic, of pregnancy | KG + DL |
| 22 | central core myopathy | KG + DL |
| 23 | congestive heart failure | KG + DL |
| 24 | moderate multiminicore disease with hand involvement | KG + DL |
| 25 | congenital multicore myopathy with external ophthalmoplegia | KG + DL |
| 26 | xerophthalmia | KG + DL |
| 27 | tumoral calcinosis, hyperphosphatemic, familial | KG + DL |
| 28 | acute pulmonary heart disease | KG + DL |
| 29 | deficiency anemia | KG + DL |
| 30 | hypoglycemia | KG + DL |
| 31 | morphine dependence | KG + DL |
| 32 | apical periodontitis | KG + DL |
| 33 | progressive familial intrahepatic cholestasis | KG + DL |
| 34 | thyrotoxic periodic paralysis | KG + DL |
| 35 | renal tubular acidosis | KG + DL |
| 36 | suppurative periapical periodontitis | KG + DL |
| 37 | periapical granuloma | KG + DL |
| 38 | hereditary angioedema with C1Inh deficiency | KG + DL |
| 39 | thyrotoxic periodic paralysis, susceptibility to | KG + DL |
| 40 | King-Denborough syndrome | KG + DL |
| 41 | familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome | KG + DL |
| 42 | intestinal obstruction | KG + DL |
| 43 | hypouricemia, renal | KG + DL |
| 44 | myopathic intestinal pseudoobstruction | KG + DL |
| 45 | unclassified intestinal pseudoobstruction | KG + DL |
| 46 | idiopathic eosinophilic myositis | KG + DL |
| 47 | inflammatory myopathy with abundant macrophages | KG + DL |
| 48 | nephrolithiasis, X-linked recessive, with renal failure | KG + DL |
| 49 | myopathy, centronuclear | KG + DL |
| 50 | serpinopathy with toxic serpin polymerization | KG + DL |
(Showing top 50 of 76 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.