Dornase Alfa
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00003 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | pyridoxine-dependent epilepsy caused by ALDH7A1 mutant | KG + DL |
| 2 | hereditary glaucoma | KG + DL |
| 3 | vaginal villous adenoma | KG + DL |
| 4 | osteoclastic giant cell tumor of pancreas | KG + DL |
| 5 | anaerobic cellulitis | KG + DL |
| 6 | glycogen storage disease due to glycogen branching enzyme deficiency, non progressive hepatic form | KG + DL |
| 7 | granulomatous hypophysitis | KG + DL |
| 8 | disease by cellular process disrupted | KG + DL |
| 9 | intermediate severe Salla disease | KG + DL |
| 10 | mesothelial neoplasm | KG + DL |
| 11 | melanocytic skin neoplasm | KG + DL |
| 12 | lymphoid hemopathy | KG + DL |
| 13 | steroid-induced glaucoma | KG + DL |
| 14 | lipomatous cancer | KG + DL |
| 15 | genetic infertility | KG + DL |
| 16 | bone marrow neoplasm | KG + DL |
| 17 | clear cell sarcoma | KG + DL |
| 18 | smooth muscle cancer | KG + DL |
| 19 | non-small cell squamous lung carcinoma | KG + DL |
| 20 | Epstein-Barr virus-associated mesenchymal tumor | KG + DL |
| 21 | generalized galactose epimerase deficiency | KG + DL |
| 22 | human herpesvirus 8-related tumor | KG + DL |
| 23 | Orthocoronavirinae infectious disease | KG + DL |
| 24 | human herpesvirus 8 infection | KG + DL |
| 25 | inner ear cancer | KG + DL |
| 26 | deafness, autosomal recessive | KG + DL |
| 27 | glycogen storage disease due to glycogen branching enzyme deficiency, adult neuromuscular form | KG + DL |
| 28 | congenital stationary night blindness autosomal dominant | KG + DL |
| 29 | Pseudomonas aeruginosa infectious disease | KG + DL |
| 30 | osteogenesis imperfecta | KG + DL |
| 31 | iodine hypothyroidism | KG + DL |
| 32 | ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies | KG + DL |
| 33 | CNS demyelinating autoimmune disease | KG + DL |
| 34 | craniosynostosis-intracranial calcifications syndrome | KG + DL |
| 35 | indolent B-cell non-Hodgkin lymphoma | KG + DL |
| 36 | arthrogryposis, distal, | KG + DL |
| 37 | autoimmune disease of gastrointestinal tract | KG + DL |
| 38 | action myoclonus-renal failure syndrome | KG + DL |
| 39 | papillary meningioma of the cerebellum | KG + DL |
| 40 | agammaglobulinemia | KG + DL |
| 41 | Bacillaceae infectious disease | KG + DL |
| 42 | bone dysplasia, lethal Holmgren type | KG + DL |
| 43 | lymphocytic hypereosinophilic syndrome | KG + DL |
| 44 | myelodysplasia, immunodeficiency, facial dysmorphism, short stature, and psychomotor delay | KG + DL |
| 45 | pleural mesothelioma | KG + DL |
| 46 | immunodeficiency-centromeric instability-facial anomalies syndrome | KG + DL |
| 47 | neurohypophysis granular cell tumor | KG + DL |
| 48 | hidrotic ectodermal dysplasia, Christianson-Fourie type | KG + DL |
| 49 | lentivirus infection | KG + DL |
| 50 | congenital nystagmus | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.